Minimally Invasive Subcortical Parafascicular Transsulcal Access for Clot Evacuation (Mi SPACE) for Intracerebral Hemorrhage

Background.Spontaneous intracerebral hemorrhage (ICH) is common and causes significant mortality and morbidity.To date, optimal medical and surgical intervention remains uncertain.A lack of definitive benefit for operative management may be attributable to adverse surgical effect, collateral tissue injury.This is particularly relevant for ICH in do

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Analysis of Pyroptosis-Related Immune Signatures and Identification of Pyroptosis-Related LncRNA Prognostic Signature in Clear Cell Renal Cell Carcinoma

Clear cell renal cell carcinoma (ccRCC) is a common urinary system malignant tumor with a high incidence and recurrence rate.Pyroptosis is a kind of Thermal Socks programmed cell death caused by inflammasomes.More and more evidence had confirmed that pyroptosis plays a very significant part in cancer, and it is controversial whether pyroptosis prom

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Nuclear RNA surveillance complexes silence HIV-1 transcription.

Expression from the HIV-1 LTR can be repressed in a small population of cells, which contributes to the latent reservoir.The factors mediating this repression Brushes have not been clearly elucidated.We have identified a network of nuclear RNA surveillance factors that act as effectors of HIV-1 silencing.RRP6, MTR4, ZCCHC8 and ZFC3H1 physically ass

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